HIV Target gene Detail Information

> SPON2 Gene Search Result

Gene Information

Gene Name	SPON2
Gene ID	10417
Gene Alias	DIL1; DIL-1; MINDIN; M-SPONDIN
Transcripts	ENSG00000159674
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Predicted to be secreted;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q9BUD6
HGNC ID	HGNC:11253
VEGA ID	OTTHUMG00000089002
OMIM ID	605918
String ID	9606.ENSP00000483599
PharmGKB ID	PA36083

Target gene [SPON2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008356	chr4	13	2		15	View
4011477	chr4	5	2		7	View
4015389	chr4	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPON2 expression and immune infiltrating cell level correlation result in HIV+ samples
SPON2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).