HIV Target gene Detail Information

> SPOCK2 Gene Search Result

Gene Information

Gene Name	SPOCK2
Gene ID	9806
Gene Full Name	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
Gene Alias	testican-2
Transcripts	ENSG00000107742
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted secreted proteins
Uniport_ID	Q92563
HGNC ID	HGNC:13564
VEGA ID	OTTHUMG00000018430
OMIM ID	607988
String ID	9606.ENSP00000362201
PharmGKB ID	PA128394560

Target gene [SPOCK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007181	chr10	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SPOCK2 expression and immune infiltrating cell level correlation result in HIV+ samples
SPOCK2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPOCK2 expression and immune infiltrating cell level correlation result in HIV+ samples
SPOCK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).