EBV Target gene Detail Information

> SPIDR Gene Search Result

Gene Information

Gene Name	SPIDR
Gene ID	23514
Gene Full Name	scaffold protein involved in DNA repair
Gene Alias	KIAA0146
Transcripts	ENSG00000164808
Virus	EBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q14159
HGNC ID	HGNC:28971
VEGA ID	OTTHUMG00000164176
OMIM ID	615384
String ID	9606.ENSP00000297423
PharmGKB ID	PA142671636

Target gene [SPIDR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000693	chr8	6			6	View
3300089	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of SPIDR expression and immune infiltrating cell level correlation result in EBV+ samples
SPIDR expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of SPIDR expression and immune infiltrating cell level correlation result in EBV+ samples
SPIDR expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of SPIDR expression and immune infiltrating cell level correlation result in EBV+ samples
SPIDR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).