HIV Target gene Detail Information

> SPHAR Gene Search Result

Gene Information

Gene Name	SPHAR
Gene ID	10638
Virus	HIV
Gene Type	protein coding
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15513
HGNC ID	HGNC:16957
VEGA ID	OTTHUMG00000058947
String ID	9606.ENSP00000355649
PharmGKB ID	PA145021510

Target gene [SPHAR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005217	chr1	11	7	17	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPHAR expression and immune infiltrating cell level correlation result in HIV+ samples
SPHAR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).