HBV Target gene Detail Information

> SPG7 Gene Search Result


Gene Information
Gene Name SPG7
Gene ID 6687
Gene Full Name SPG7, paraplegin matrix AAA peptidase subunit
Gene Alias CAR; PGN; CMAR; SPG5C
Transcripts ENSG00000197912
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9UQ90
HGNC ID HGNC:11237
VEGA ID OTTHUMG00000138046
OMIM ID 602783
String ID 9606.ENSP00000268704
PharmGKB ID PA36067
Target gene [SPG7] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002266 chr16 304 304 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SPG7 expression and immune infiltrating cell level correlation result in HBV+ samples
SPG7 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).