HBV Target gene Detail Information

> SPG11 Gene Search Result

Gene Information

Gene Name	SPG11
Gene ID	80208
Gene Full Name	SPG11, spatacsin vesicle trafficking associated
Gene Alias	ALS5; CMT2X; KIAA1840
Transcripts	ENSG00000104133
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Nucleoli;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q96JI7
HGNC ID	HGNC:11226
VEGA ID	OTTHUMG00000131199
OMIM ID	610844
String ID	9606.ENSP00000261866
PharmGKB ID	PA36058

Target gene [SPG11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012936	chr15	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SPG11 expression and immune infiltrating cell level correlation result in HBV+ samples
SPG11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).