HBV Target gene Detail Information

> SPEF2 Gene Search Result


Gene Information
Gene Name SPEF2
Gene ID 79925
Gene Full Name sperm flagellar 2
Gene Alias KPL2; CT122
Transcripts ENSG00000152582
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9C093
HGNC ID HGNC:26293
VEGA ID OTTHUMG00000131111
OMIM ID 610172
String ID 9606.ENSP00000348314
PharmGKB ID PA162404451
Target gene [SPEF2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009286 chr5 10 6 16 View
1400484 chr5 4 4 View
1403292 chr5 10 6 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SPEF2 expression and immune infiltrating cell level correlation result in HBV+ samples
SPEF2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).