Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> SPECC1 Gene Search Result


Gene Information
Gene Name SPECC1
Gene ID 92521
Gene Full Name sperm antigen with calponin homology and coiled-coil domains 1
Gene Alias NSP; CYTSB; HCMOGT1; HCMOGT-1
Transcripts ENSG00000128487
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;Cytosol;Nucleoli fibrillar center;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q5M775
HGNC ID HGNC:30615
VEGA ID OTTHUMG00000179808
OMIM ID 608793
String ID 9606.ENSP00000261503
PharmGKB ID PA164718712
Target gene [SPECC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003977 chr17 43 52 4 99 View
1010920 chr17 4 5 1 10 View
1403007 chr17 4 5 1 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SPECC1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SPECC1 expression: Low -> High
Lollipop of SPECC1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SPECC1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).