HIV Target gene Detail Information

> SPC24 Gene Search Result

Gene Information

Gene Name	SPC24
Gene ID	147841
Gene Full Name	SPC24, NDC80 kinetochore complex component
Gene Alias	SPBC24
Transcripts	ENSG00000161888
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NBT2
HGNC ID	HGNC:26913
VEGA ID	OTTHUMG00000180798
OMIM ID	609394
String ID	9606.ENSP00000465075
PharmGKB ID	PA162404412

Target gene [SPC24] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006826	chr19	19	1	2	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SPC24 expression and immune infiltrating cell level correlation result in HIV+ samples
SPC24 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPC24 expression and immune infiltrating cell level correlation result in HIV+ samples
SPC24 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).