HIV Target gene Detail Information

> SPATS2 Gene Search Result

Gene Information

Gene Name	SPATS2
Gene ID	65244
Gene Full Name	spermatogenesis associated serine rich 2
Gene Alias	SCR59; P59SCR; SPATA10; Nbla00526
Transcripts	ENSG00000123352
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q86XZ4
HGNC ID	HGNC:18650
VEGA ID	OTTHUMG00000169419
OMIM ID	611667
String ID	9606.ENSP00000448228
PharmGKB ID	PA134871579

Target gene [SPATS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002472	chr12	86	3	4	93	View
4002473	chr12	86	3	4	93	View
4002474	chr12	86	3	4	93	View
4002475	chr12	86	3	4	93	View
4005161	chr12	15	10	10	35	View
4007398	chr12	5	14		19	View
4007652	chr12	16	2		18	View
4009732	chr12	5	6		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SPATS2 expression and immune infiltrating cell level correlation result in HIV+ samples
SPATS2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPATS2 expression and immune infiltrating cell level correlation result in HIV+ samples
SPATS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).