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HTLV1 Target gene Detail Information

> SPATA4 Gene Search Result


Gene Information
Gene Name SPATA4
Gene ID 132851
Gene Full Name spermatogenesis associated 4
Gene Alias SPEF1B; TSARG2
Transcripts ENSG00000150628
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q8NEY3
HGNC ID HGNC:17333
VEGA ID OTTHUMG00000160788
OMIM ID 609879
String ID 9606.ENSP00000280191
PharmGKB ID PA38232
Target gene [SPATA4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6004477 chr4 44 30 40 114 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SPATA4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SPATA4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SPATA4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).