HTLV1 Target gene Detail Information

> SPATA16 Gene Search Result


Gene Information
Gene Name SPATA16
Gene ID 83893
Gene Full Name spermatogenesis associated 16
Gene Alias SPGF6; NYD-SP12
Transcripts ENSG00000144962
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q9BXB7
HGNC ID HGNC:29935
VEGA ID OTTHUMG00000156865
OMIM ID 609856
String ID 9606.ENSP00000341765
PharmGKB ID PA134942358
Target gene [SPATA16] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003468 chr3 43 45 70 158 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SPATA16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA16 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SPATA16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA16 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SPATA16 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SPATA16 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).