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HPV Target gene Detail Information

> SPATA12 Gene Search Result


Gene Information
Gene Name SPATA12
Gene ID 353324
Gene Full Name spermatogenesis associated 12
Gene Alias SRG5
Transcripts ENSG00000186451
Virus HPV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q7Z6I5
HGNC ID HGNC:23221
VEGA ID OTTHUMG00000158862
OMIM ID 609869
String ID 9606.ENSP00000335392
PharmGKB ID PA134888733
Target gene [SPATA12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000097 chr3 577 1030 837 2444 View
5000105 chr3 710 902 676 2288 View
5002675 chr3 5 4 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of SPATA12 expression and immune infiltrating cell level correlation result in HPV+ samples
SPATA12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).