HIV Target gene Detail Information

> SPAG9 Gene Search Result

Gene Information

Gene Name	SPAG9
Gene ID	9043
Gene Full Name	sperm associated antigen 9
Gene Alias	JLP; CT89; HLC4; HLC6; JIP4; PHET; PIG6; HLC-6; JIP-4
Transcripts	ENSG00000008294
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	O60271
HGNC ID	HGNC:14524
VEGA ID	OTTHUMG00000162316
OMIM ID	605430
String ID	9606.ENSP00000262013
PharmGKB ID	PA37890

Target gene [SPAG9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004742	chr17	35	5		40	View
4007405	chr17	13	5	1	19	View
4016088	chr17				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SPAG9 expression and immune infiltrating cell level correlation result in HIV+ samples
SPAG9 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SPAG9 expression and immune infiltrating cell level correlation result in HIV+ samples
SPAG9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).