HIV Target gene Detail Information

> SP140L Gene Search Result

Gene Information

Gene Name	SP140L
Gene ID	93349
Gene Full Name	SP140 nuclear body protein like
Transcripts	ENSG00000185404
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9H930
HGNC ID	HGNC:25105
VEGA ID	OTTHUMG00000153730
OMIM ID	617747
String ID	9606.ENSP00000397911
PharmGKB ID	PA164726206

Target gene [SP140L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006846	chr2	21	1		22	View
4007674	chr2	16	2		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SP140L expression and immune infiltrating cell level correlation result in HIV+ samples
SP140L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SP140L expression and immune infiltrating cell level correlation result in HIV+ samples
SP140L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).