HIV Target gene Detail Information

> SP100 Gene Search Result

Gene Information

Gene Name	SP100
Gene ID	6672
Gene Full Name	SP100 nuclear antigen
Gene Alias	lysp100b
Transcripts	ENSG00000067066
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P23497
HGNC ID	HGNC:11206
VEGA ID	OTTHUMG00000133203
OMIM ID	604585
String ID	9606.ENSP00000343023
PharmGKB ID	PA36043

Target gene [SP100] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002921	chr2	64	7	4	75	View
4003236	chr2	65	1		66	View
4005709	chr2	21	8	1	30	View
4009952	chr2	7	3		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SP100 expression and immune infiltrating cell level correlation result in HIV+ samples
SP100 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SP100 expression and immune infiltrating cell level correlation result in HIV+ samples
SP100 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).