HPV Target gene Detail Information

> SOX30 Gene Search Result


Gene Information
Gene Name SOX30
Gene ID 11063
Gene Full Name SRY-box 30
Transcripts ENSG00000039600
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID O94993
HGNC ID HGNC:30635
VEGA ID OTTHUMG00000130247
OMIM ID 606698
String ID 9606.ENSP00000265007
PharmGKB ID PA134876614
Target gene [SOX30] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402710 chr5 6 1 2 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of SOX30 expression and immune infiltrating cell level correlation result in HPV+ samples
SOX30 expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of SOX30 expression and immune infiltrating cell level correlation result in HPV+ samples
SOX30 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).