HPV Target gene Detail Information

> SOX2-OT Gene Search Result


Gene Information
Gene Name SOX2-OT
Gene ID 347689
Gene Alias SOX2OT; NCRNA00043
Transcripts ENSG00000242808
Virus HPV
Gene Type ncRNA
HPA Location Info
HGNC ID HGNC:20209
VEGA ID OTTHUMG00000158186
OMIM ID 616338
lncRNASNP2 ID NONHSAG036783.2
PharmGKB ID PA134874116
Target gene [SOX2-OT] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002870 chr3 5 2 7 View
5004458 chr3 0 View
5200145 chr3 2 2 View
5200341 chr3 9 9 View
5201225 chr3 8 8 View
5400882 chr3 15 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of SOX2-OT expression and immune infiltrating cell level correlation result in HPV+ samples
SOX2-OT expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of SOX2-OT expression and immune infiltrating cell level correlation result in HPV+ samples
SOX2-OT expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of SOX2-OT expression and immune infiltrating cell level correlation result in HPV+ samples
SOX2-OT expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of SOX2-OT expression and immune infiltrating cell level correlation result in HPV+ samples
SOX2-OT expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).