HBV Target gene Detail Information

> SORL1 Gene Search Result

Gene Information

Gene Name	SORL1
Gene ID	6653
Gene Full Name	sortilin related receptor 1
Gene Alias	LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32
Transcripts	ENSG00000137642
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	Q92673
HGNC ID	HGNC:11185
VEGA ID	OTTHUMG00000166057
OMIM ID	602005
String ID	9606.ENSP00000260197
PharmGKB ID	PA36022

Target gene [SORL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004591	chr11	74	2		76	View
1007446	chr11	20	7		27	View
1010308	chr11	4	3	5	12	View
1010459	chr11	8	3	1	12	View
1403726	chr11	4	3	5	12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SORL1 expression and immune infiltrating cell level correlation result in HBV+ samples
SORL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).