HBV Target gene Detail Information

> SORCS1 Gene Search Result


Gene Information
Gene Name SORCS1
Gene ID 114815
Gene Full Name sortilin related VPS10 domain containing receptor 1
Gene Alias hSorCS
Transcripts ENSG00000108018
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q8WY21
HGNC ID HGNC:16697
VEGA ID OTTHUMG00000019018
OMIM ID 606283
String ID 9606.ENSP00000263054
PharmGKB ID PA134861284
Target gene [SORCS1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005687 chr10 44 5 49 View
1400942 chr10 44 5 49 View
1404676 chr10 690 1000 436 2126 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SORCS1 expression and immune infiltrating cell level correlation result in HBV+ samples
SORCS1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).