HBV Target gene Detail Information

> SORBS1 Gene Search Result

Gene Information

Gene Name	SORBS1
Gene ID	10580
Gene Full Name	sorbin and SH3 domain containing 1
Gene Alias	CAP; FLAF2; R85FL; SH3D5; SORB1; SH3P12
Transcripts	ENSG00000095637
Virus	HBV
Gene Type	protein coding
HPA Location Info	Focal adhesion sites;Centrosome;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9BX66
HGNC ID	HGNC:14565
VEGA ID	OTTHUMG00000018812
OMIM ID	605264
String ID	9606.ENSP00000360293
PharmGKB ID	PA37899

Target gene [SORBS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011444	chr10	8	1		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SORBS1 expression and immune infiltrating cell level correlation result in HBV+ samples
SORBS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).