HIV Target gene Detail Information

> SON Gene Search Result

Gene Information

Gene Name	SON
Gene ID	6651
Gene Full Name	SON DNA binding protein
Gene Alias	SON3; BASS1; DBP-5; NREBP; TOKIMS; C21orf50
Transcripts	ENSG00000159140
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	P18583
HGNC ID	HGNC:11183
VEGA ID	OTTHUMG00000065806
OMIM ID	182465
String ID	9606.ENSP00000348984
PharmGKB ID	PA36020

Target gene [SON] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002970	chr21	35	27	11	73	View
4005432	chr21	30	3		33	View
4006885	chr21	2	10	10	22	View
4009844	chr21	9	1		10	View
4014753	chr21		2		2	View
4014754	chr21	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SON expression and immune infiltrating cell level correlation result in HIV+ samples
SON expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SON expression and immune infiltrating cell level correlation result in HIV+ samples
SON expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).