HBV Target gene Detail Information

> SOD2 Gene Search Result

Gene Information

Gene Name	SOD2
Gene ID	6648
Gene Full Name	superoxide dismutase 2
Gene Alias	IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD
Transcripts	ENSG00000112096
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
HGNC ID	HGNC:11180
VEGA ID	OTTHUMG00000015940
OMIM ID	147460
String ID	9606.ENSP00000446252
Drugbank ID	BE0004453
PharmGKB ID	PA36017

Target gene [SOD2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000271	chr6	1143	1153	936	3232	View
1006722	chr6	30	4	1	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SOD2 expression and immune infiltrating cell level correlation result in HBV+ samples
SOD2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).