HBV Target gene Detail Information

> SOD2 Gene Search Result


Gene Information
Gene Name SOD2
Gene ID 6648
Gene Full Name superoxide dismutase 2
Gene Alias IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD
Transcripts ENSG00000112096
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
HGNC ID HGNC:11180
VEGA ID OTTHUMG00000015940
OMIM ID 147460
String ID 9606.ENSP00000446252
Drugbank ID BE0004453
PharmGKB ID PA36017
Target gene [SOD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000271 chr6 1143 1153 936 3232 View
1006722 chr6 30 4 1 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SOD2 expression and immune infiltrating cell level correlation result in HBV+ samples
SOD2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).