HBV Target gene Detail Information

> SOD1 Gene Search Result

Gene Information

Gene Name	SOD1
Gene ID	6647
Gene Full Name	superoxide dismutase 1
Gene Alias	ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer
Transcripts	ENSG00000142168
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P00441
HGNC ID	HGNC:11179
VEGA ID	OTTHUMG00000084878
OMIM ID	147450
String ID	9606.ENSP00000270142
Drugbank ID	BE0002390
PharmGKB ID	PA334

Target gene [SOD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007025	chr21	31			31	View
1400481	chr21	8	3		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SOD1 expression and immune infiltrating cell level correlation result in HBV+ samples
SOD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).