HIV Target gene Detail Information

> SOCS7 Gene Search Result

Gene Information

Gene Name	SOCS7
Gene ID	30837
Gene Full Name	suppressor of cytokine signaling 7
Gene Alias	NAP4; NCKAP4
Transcripts	ENSG00000274229
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O14512
HGNC ID	HGNC:29846
VEGA ID	OTTHUMG00000191264
OMIM ID	608788
String ID	9606.ENSP00000482229
PharmGKB ID	PA164742488

Target gene [SOCS7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003086	chr17	16	43	11	70	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SOCS7 expression and immune infiltrating cell level correlation result in HIV+ samples
SOCS7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).