HIV Target gene Detail Information

> SOCS5 Gene Search Result

Gene Information

Gene Name	SOCS5
Gene ID	9655
Gene Full Name	suppressor of cytokine signaling 5
Gene Alias	CIS6; CISH6; Cish5; SOCS-5
Transcripts	ENSG00000171150
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75159
HGNC ID	HGNC:16852
VEGA ID	OTTHUMG00000128852
OMIM ID	607094
String ID	9606.ENSP00000305133
PharmGKB ID	PA134884627

Target gene [SOCS5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011322	chr2	5	1	1	7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SOCS5 expression and immune infiltrating cell level correlation result in HIV+ samples
SOCS5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).