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HBV Target gene Detail Information

> SNX6 Gene Search Result


Gene Information
Gene Name SNX6
Gene ID 58533
Gene Full Name sorting nexin 6
Gene Alias TFAF2; MSTP010
Transcripts ENSG00000129515
Virus HBV
Gene Type protein coding
HPA Location Info Endosomes;Lysosomes;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9UNH7
HGNC ID HGNC:14970
VEGA ID OTTHUMG00000140213
OMIM ID 606098
String ID 9606.ENSP00000355217
PharmGKB ID PA37946
Target gene [SNX6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002732 chr14 18 84 113 215 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SNX6 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SNX6 expression: Low -> High
Lollipop of SNX6 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SNX6 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SNX6 expression and immune infiltrating cell level correlation result in HBV+ samples
SNX6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).