HIV Target gene Detail Information

> SNX4 Gene Search Result


Gene Information
Gene Name SNX4
Gene ID 8723
Gene Full Name sorting nexin 4
Gene Alias ATG24B
Transcripts ENSG00000114520
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O95219
HGNC ID HGNC:11175
VEGA ID OTTHUMG00000159575
OMIM ID 605931
String ID 9606.ENSP00000251775
PharmGKB ID PA36014
Target gene [SNX4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005847 chr3 3 18 8 29 View
4012548 chr3 5 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SNX4 expression and immune infiltrating cell level correlation result in HIV+ samples
SNX4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SNX4 expression and immune infiltrating cell level correlation result in HIV+ samples
SNX4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).