HIV Target gene Detail Information

> SNTB2 Gene Search Result

Gene Information

Gene Name	SNTB2
Gene ID	6645
Gene Full Name	syntrophin beta 2
Gene Alias	SNT3; SNTL; SNT2B2; EST25263; D16S2531E
Transcripts	ENSG00000260873
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13425
HGNC ID	HGNC:11169
VEGA ID	OTTHUMG00000174907
OMIM ID	600027
String ID	9606.ENSP00000338191
PharmGKB ID	PA36009

Target gene [SNTB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000918	chr16	35	124	90	249	View
4001659	chr16	59	9	75	143	View
4010404	chr16	5	4		9	View
4011989	chr16	5	1		6	View
4013440	chr16		3		3	View
4015172	chr16	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SNTB2 expression and immune infiltrating cell level correlation result in HIV+ samples
SNTB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SNTB2 expression and immune infiltrating cell level correlation result in HIV+ samples
SNTB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).