HTLV1 Target gene Detail Information

> SNRPC Gene Search Result


Gene Information
Gene Name SNRPC
Gene ID 6631
Gene Full Name small nuclear ribonucleoprotein polypeptide C
Gene Alias U1C; Yhc1
Transcripts ENSG00000124562
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P09234
HGNC ID HGNC:11157
VEGA ID OTTHUMG00000014555
OMIM ID 603522
String ID 9606.ENSP00000244520
PharmGKB ID PA35998
Target gene [SNRPC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005722 chr6 19 10 53 82 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SNRPC expression and immune infiltrating cell level correlation result in HTLV1+ samples
SNRPC expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SNRPC expression and immune infiltrating cell level correlation result in HTLV1+ samples
SNRPC expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SNRPC expression and immune infiltrating cell level correlation result in HTLV1+ samples
SNRPC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).