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HBV Target gene Detail Information

> SMYD3 Gene Search Result


Gene Information
Gene Name SMYD3
Gene ID 64754
Gene Full Name SET and MYND domain containing 3
Gene Alias KMT3E; ZMYND1; ZNFN3A1; bA74P14.1
Transcripts ENSG00000185420
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID Q9H7B4
HGNC ID HGNC:15513
VEGA ID OTTHUMG00000040508
OMIM ID 608783
String ID 9606.ENSP00000419184
PharmGKB ID PA37972
Target gene [SMYD3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003888 chr1 32 57 14 103 View
1003969 chr1 48 48 3 99 View
1012260 chr1 3 4 7 View
1013858 chr1 2 2 4 View
1401293 chr1 32 57 14 103 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SMYD3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SMYD3 expression: Low -> High
Lollipop of SMYD3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SMYD3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SMYD3 expression and immune infiltrating cell level correlation result in HBV+ samples
SMYD3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).