HIV Target gene Detail Information

> SMURF2 Gene Search Result

Gene Information

Gene Name	SMURF2
Gene ID	64750
Gene Full Name	SMAD specific E3 ubiquitin protein ligase 2
Transcripts	ENSG00000108854
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9HAU4
HGNC ID	HGNC:16809
VEGA ID	OTTHUMG00000179189
OMIM ID	605532
String ID	9606.ENSP00000262435
PharmGKB ID	PA134985524

Target gene [SMURF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001497	chr17	118	34	5	157	View
4002613	chr17	67	12	8	87	View
4003201	chr17	26	3	38	67	View
4004119	chr17	48	1		49	View
4004235	chr17	5	38	4	47	View
4006048	chr17	4	6	17	27	View
4009455	chr17	9		2	11	View
4010204	chr17	9			9	View
4010301	chr17	6	3		9	View
4012920	chr17	4			4	View
4013251	chr17	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMURF2 expression and immune infiltrating cell level correlation result in HIV+ samples
SMURF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).