HIV Target gene Detail Information

> SMPD3 Gene Search Result

Gene Information

Gene Name	SMPD3
Gene ID	55512
Gene Full Name	sphingomyelin phosphodiesterase 3
Gene Alias	NSMASE2
Transcripts	ENSG00000103056
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NY59
HGNC ID	HGNC:14240
VEGA ID	OTTHUMG00000137559
OMIM ID	605777
String ID	9606.ENSP00000219334
Drugbank ID	BE0002301
PharmGKB ID	PA37862

Target gene [SMPD3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002167	chr16	88	18	2	108	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMPD3 expression and immune infiltrating cell level correlation result in HIV+ samples
SMPD3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).