HIV Target gene Detail Information

> SMG7 Gene Search Result

Gene Information

Gene Name	SMG7
Gene ID	9887
Gene Full Name	SMG7, nonsense mediated mRNA decay factor
Gene Alias	EST1C; SGA56M; C1orf16
Transcripts	ENSG00000116698
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Intermediate filaments;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q92540
HGNC ID	HGNC:16792
VEGA ID	OTTHUMG00000035221
OMIM ID	610964
String ID	9606.ENSP00000425133
PharmGKB ID	PA25605

Target gene [SMG7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006161	chr1	5	14	7	26	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMG7 expression and immune infiltrating cell level correlation result in HIV+ samples
SMG7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SMG7 expression and immune infiltrating cell level correlation result in HIV+ samples
SMG7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).