HBV Target gene Detail Information

> SMG6 Gene Search Result

Gene Information

Gene Name	SMG6
Gene ID	23293
Gene Full Name	SMG6, nonsense mediated mRNA decay factor
Gene Alias	EST1A; SMG-6; C17orf31; hSMG5/7a
Transcripts	ENSG00000070366
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q86US8
HGNC ID	HGNC:17809
VEGA ID	OTTHUMG00000177578
OMIM ID	610963
String ID	9606.ENSP00000263073
Drugbank ID	BE0002478
PharmGKB ID	PA25584

Target gene [SMG6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011433	chr17	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SMG6 expression and immune infiltrating cell level correlation result in HBV+ samples
SMG6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).