HBV Target gene Detail Information

> SMG5 Gene Search Result

Gene Information

Gene Name	SMG5
Gene ID	23381
Gene Full Name	SMG5, nonsense mediated mRNA decay factor
Gene Alias	EST1B; SMG-5; LPTSRP1; LPTS-RP1
Transcripts	ENSG00000198952
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytoplasmic bodies;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9UPR3
HGNC ID	HGNC:24644
VEGA ID	OTTHUMG00000017491
OMIM ID	610962
String ID	9606.ENSP00000355261
PharmGKB ID	PA143485617

Target gene [SMG5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008149	chr1	20	1	1	22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SMG5 expression and immune infiltrating cell level correlation result in HBV+ samples
SMG5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).