HIV Target gene Detail Information

> SMG1 Gene Search Result


Gene Information
Gene Name SMG1
Gene ID 23049
Gene Full Name SMG1, nonsense mediated mRNA decay associated PI3K related kinase
Gene Alias ATX; LIP; 61E3.4
Transcripts ENSG00000157106
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q96Q15
HGNC ID HGNC:30045
VEGA ID OTTHUMG00000166900
OMIM ID 607032
String ID 9606.ENSP00000402515
PharmGKB ID PA164725852
Target gene [SMG1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000705 chr16 280 19 11 310 View
4001133 chr16 46 69 92 207 View
4001396 chr16 156 13 169 View
4002107 chr16 110 2 112 View
4005601 chr16 27 4 31 View
4006681 chr16 23 23 View
4006718 chr16 23 23 View
4007127 chr16 21 21 View
4007128 chr16 21 21 View
4007129 chr16 21 21 View
4007130 chr16 21 21 View
4007131 chr16 21 21 View
4007133 chr16 21 21 View
4007134 chr16 21 21 View
4007135 chr16 21 21 View
4007136 chr16 21 21 View
4009228 chr16 12 12 View
4012238 chr16 4 1 5 View
4015517 chr16 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SMG1 expression and immune infiltrating cell level correlation result in HIV+ samples
SMG1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).