HIV Target gene Detail Information

> SMC5 Gene Search Result

Gene Information

Gene Name	SMC5
Gene ID	23137
Gene Full Name	structural maintenance of chromosomes 5
Gene Alias	SMC5L1
Transcripts	ENSG00000198887
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IY18
HGNC ID	HGNC:20465
VEGA ID	OTTHUMG00000019992
OMIM ID	609386
String ID	9606.ENSP00000354957
PharmGKB ID	PA134993662

Target gene [SMC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006838	chr9	17	5		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMC5 expression and immune infiltrating cell level correlation result in HIV+ samples
SMC5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).