HIV Target gene Detail Information

> SMC1B Gene Search Result

Gene Information

Gene Name	SMC1B
Gene ID	27127
Gene Full Name	structural maintenance of chromosomes 1B
Gene Alias	SMC1L2; SMC1BETA
Transcripts	ENSG00000077935
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NDV3
HGNC ID	HGNC:11112
VEGA ID	OTTHUMG00000151334
OMIM ID	608685
String ID	9606.ENSP00000350036
PharmGKB ID	PA35962

Target gene [SMC1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004405	chr22	43	2		45	View
4004406	chr22	43	2		45	View
4004470	chr22	42	2		44	View
4005230	chr22	34	1		35	View
4007150	chr22	20	1		21	View
4015361	chr22	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMC1B expression and immune infiltrating cell level correlation result in HIV+ samples
SMC1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).