HIV Target gene Detail Information

> SMARCE1 Gene Search Result

Gene Information

Gene Name	SMARCE1
Gene ID	6605
Gene Full Name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Gene Alias	CSS5; BAF57
Transcripts	ENSG00000073584
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q969G3
HGNC ID	HGNC:11109
VEGA ID	OTTHUMG00000133367
OMIM ID	603111
String ID	9606.ENSP00000323967
Drugbank ID	BE0008960
PharmGKB ID	PA35959

Target gene [SMARCE1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005383	chr17	32	1		33	View
4006609	chr17	19	5		24	View
4007557	chr17	14	1	4	19	View
4008232	chr17	16			16	View
4009075	chr17	12	1		13	View
4009143	chr17	8	4		12	View
4009379	chr17	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMARCE1 expression and immune infiltrating cell level correlation result in HIV+ samples
SMARCE1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SMARCE1 expression and immune infiltrating cell level correlation result in HIV+ samples
SMARCE1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).