HBV Target gene Detail Information

> SMARCC1 Gene Search Result


Gene Information
Gene Name SMARCC1
Gene ID 6599
Gene Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
Gene Alias Rsc8; SRG3; SWI3; BAF155; CRACC1
Transcripts ENSG00000173473
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function Suppressor gene
Uniport_ID Q92922
HGNC ID HGNC:11104
VEGA ID OTTHUMG00000133519
OMIM ID 601732
String ID 9606.ENSP00000254480
PharmGKB ID PA35954
Target gene [SMARCC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006503 chr3 21 12 4 37 View
1006905 chr3 21 11 32 View
1401702 chr3 21 12 4 37 View
1401703 chr3 21 11 32 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SMARCC1 expression and immune infiltrating cell level correlation result in HBV+ samples
SMARCC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).