HBV Target gene Detail Information

> SMARCB1 Gene Search Result


Gene Information
Gene Name SMARCB1
Gene ID 6598
Gene Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Gene Alias RDT; CSS3; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; PPP1R144
Transcripts ENSG00000275837
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nucleoli fibrillar center;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q12824
HGNC ID HGNC:11103
VEGA ID OTTHUMG00000190063
OMIM ID 601607
String ID 9606.ENSP00000263121
PharmGKB ID PA35953
Target gene [SMARCB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1013219 chr22 5 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SMARCB1 expression and immune infiltrating cell level correlation result in HBV+ samples
SMARCB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).