HIV Target gene Detail Information

> SMAP2 Gene Search Result

Gene Information

Gene Name	SMAP2
Gene ID	64744
Gene Full Name	small ArfGAP2
Gene Alias	SMAP1L
Transcripts	ENSG00000084070
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WU79
HGNC ID	HGNC:25082
VEGA ID	OTTHUMG00000007301
OMIM ID	616916
String ID	9606.ENSP00000361803
PharmGKB ID	PA162403939

Target gene [SMAP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000967	chr1	4	47	186	237	View
4005193	chr1	33	2		35	View
4005684	chr1	27	1	2	30	View
4013830	chr1	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SMAP2 expression and immune infiltrating cell level correlation result in HIV+ samples
SMAP2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SMAP2 expression and immune infiltrating cell level correlation result in HIV+ samples
SMAP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).