HBV Target gene Detail Information

> SMAD9 Gene Search Result

Gene Information

Gene Name	SMAD9
Gene ID	4093
Gene Full Name	SMAD family member 9
Gene Alias	PPH2; MADH6; MADH9; SMAD8; SMAD8A; SMAD8B; SMAD8/9
Transcripts	ENSG00000120693
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	O15198
HGNC ID	HGNC:6774
VEGA ID	OTTHUMG00000016740
OMIM ID	603295
String ID	9606.ENSP00000369154
PharmGKB ID	PA30531

Target gene [SMAD9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010837	chr13	11			11	View
1011264	chr13	5	4		9	View
1403631	chr13	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SMAD9 expression and immune infiltrating cell level correlation result in HBV+ samples
SMAD9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).