HIV Target gene Detail Information

> SLX4 Gene Search Result

Gene Information

Gene Name	SLX4
Gene ID	84464
Gene Full Name	SLX4 structure-specific endonuclease subunit
Gene Alias	FANCP; BTBD12; MUS312
Transcripts	ENSG00000188827
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cell Junctions;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q8IY92
HGNC ID	HGNC:23845
VEGA ID	OTTHUMG00000074089
OMIM ID	613278
String ID	9606.ENSP00000294008
PharmGKB ID	PA134983583

Target gene [SLX4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004948	chr16	16	14	7	37	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLX4 expression and immune infiltrating cell level correlation result in HIV+ samples
SLX4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).