HIV Target gene Detail Information

> SLTM Gene Search Result


Gene Information
Gene Name SLTM
Gene ID 79811
Gene Full Name SAFB like transcription modulator
Gene Alias Met
Transcripts ENSG00000137776
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NWH9
HGNC ID HGNC:20709
VEGA ID OTTHUMG00000074033
String ID 9606.ENSP00000369887
PharmGKB ID PA142670898
Target gene [SLTM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002219 chr15 91 10 4 105 View
4006328 chr15 2 18 5 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SLTM expression and immune infiltrating cell level correlation result in HIV+ samples
SLTM expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SLTM expression and immune infiltrating cell level correlation result in HIV+ samples
SLTM expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).