HIV Target gene Detail Information

> SLIT2 Gene Search Result

Gene Information

Gene Name	SLIT2
Gene ID	9353
Gene Full Name	slit guidance ligand 2
Gene Alias	SLIL3; Slit-2
Transcripts	ENSG00000145147
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Gene Function	Suppressor gene
Uniport_ID	O94813
HGNC ID	HGNC:11086
VEGA ID	OTTHUMG00000128551
OMIM ID	603746
String ID	9606.ENSP00000422591
PharmGKB ID	PA35939

Target gene [SLIT2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003483	chr4	38	4	18	60	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLIT2 expression and immune infiltrating cell level correlation result in HIV+ samples
SLIT2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).