HTLV1 Target gene Detail Information

> SLFN13 Gene Search Result

Gene Information

Gene Name	SLFN13
Gene ID	146857
Gene Full Name	schlafen family member 13
Gene Alias	SLFN10; hSLFN13
Transcripts	ENSG00000154760
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytokinetic bridge;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q68D06
HGNC ID	HGNC:26481
VEGA ID	OTTHUMG00000165108
OMIM ID	614957
String ID	9606.ENSP00000285013
PharmGKB ID	PA144596360

Target gene [SLFN13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6012381	chr17	13	10		23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SLFN13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLFN13 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of SLFN13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLFN13 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of SLFN13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLFN13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).