Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> SLCO1B1 Gene Search Result


Gene Information
Gene Name SLCO1B1
Gene ID 10599
Gene Full Name solute carrier organic anion transporter family member 1B1
Gene Alias LST1; HBLRR; LST-1; OATP2; OATPC; OATP-C; OATP1B1; SLC21A6
Transcripts ENSG00000134538
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID Q9Y6L6
HGNC ID HGNC:10959
VEGA ID OTTHUMG00000169047
OMIM ID 604843
String ID 9606.ENSP00000256958
Drugbank ID BE0001004
Drug (Cytoscape Annotation) Paclitaxel
PharmGKB ID PA134865839
FDA Approved Drug Elagolix;Rosuvastatin
Target gene [SLCO1B1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006349 chr12 38 3 41 View
1007573 chr12 14 12 26 View
1015148 chr12 3 3 View
1019958 chr12 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLCO1B1 expression and immune infiltrating cell level correlation result in HBV+ samples
SLCO1B1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).