HIV Target gene Detail Information

> SLC9A8 Gene Search Result

Gene Information

Gene Name	SLC9A8
Gene ID	23315
Gene Full Name	solute carrier family 9 member A8
Gene Alias	NHE8; NHE-8
Transcripts	ENSG00000197818
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y2E8
HGNC ID	HGNC:20728
VEGA ID	OTTHUMG00000032710
OMIM ID	612730
String ID	9606.ENSP00000416418
PharmGKB ID	PA134924114

Target gene [SLC9A8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003188	chr20	63	1	3	67	View
4004210	chr20	46	1		47	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC9A8 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC9A8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC9A8 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC9A8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).